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Research Update #49

Welcome to Research Update, our monthly summary of important and interesting contact lens-related papers published in the peer-reviewed literature

Special Issue – January 2021

We wish you a very happy new year and bring to you the first issue of our monthly Research Update of 2021! 

The contact lens (CL) world has always been intrigued by how the eye responds to CL wear. The arrival of silicone hydrogel lenses significantly reduced several complications related to ocular surface hypoxia and daily disposable soft contact lenses improved ocular hygiene. Nonetheless, it is important that clinicians remain vigilant to changes related to contact lens adaptation and complications.

‘The papers presented in this special issue of Contact Lens and Anterior Eye provide a snapshot of the major areas of ongoing research in the important area of safety and compatibility during contact lens wear,’ say the guest editors of this special issue on ‘adaptation and adverse responses to contact lens wear.’ 

Here are some excerpts from the issue with links to the full text.

The IACLE Education Team


Journal reviewed in this issue:

Contact Lens & Anterior Eye 44:1


Eye fatigue and digital devices

To quantify the relationship amongst symptoms most frequently associated with eye fatigue in those using digital devices, Meyer et al recruited 602 soft contact lens (SCL) wearers and 127 non-contact lens (non-CL) wearers (digital devices usage of minimum 4 hours per day). They completed a questionnaire assessing the frequency and severity of ten symptoms commonly associated with digital device-related eye fatigue. Frequent and severe eye fatigue was highly prevalent among both the groups. Those wearing SCL did not experience symptoms at higher frequency or severity. 

Cont Lens Anterior Eye 2020;44:1 42-50. Read the full text


Eyelid warming masks and dry eye

This prospective, randomized, active-controlled trial was conducted by Jeon and Park to compare the efficacy of artificial tears and warm compresses with an eyelid warming mask (EWM) in alleviating dry eye disease (DED) in 81 young adult CL wearers. Participants were randomly categorized into three groups - artificial tear group, EWM group and control. EWM and artificial tears showed similar effects in terms of increased tear secretion and relief from ocular discomfort among CL wearers. The authors concluded that applying a warm compress with EWM can be recommended as a treatment for DED in CL wearers.

Cont Lens Anterior Eye 2020;44:1 30-34. Read the full text


Non adherence to contact lens wear schedule in children

To determine factors associated with non-adherence to CL wear schedule involving single vision and myopia control CLs in children, Wend et al included data of 379 children enrolled in a clinical trial. The children wore either: single vision silicone hydrogel CL (control lens) or myopia control lenses (test lenses). Non-adherence was greater in those who discontinued during the study. Subjective ratings of visual quality were lower and ocular comfort was poorer in non-adherent wearers. Paying attention to these factors and taking steps to ensure satisfaction in lens wear may promote longer term continuation of wear. 

Cont Lens Anterior Eye 2020;44:1 94-101. Read the full text


The contact lens risk survey

This multi-centre, case-control, prospective study was conducted by Mickles et al to test the Contact Lens Risk Survey (CLRS) scoring algorithm in soft contact lens (SCL) wearers presenting with SCL-related adverse events, and healthy matched controls. A total of 171 SCL wearers were enrolled - 57 cases (symptomatic red eyes) and 114 controls. Cases were classified as CL related serious and significant or non-serious events. The CLRS scoring system showed excellent discrimination between serious and significant cases and both non-serious and significant cases and healthy SCL controls. CLRS scoring system could help practitioners identify patients at greatest risk for CL-related adverse events.

Cont Lens Anterior Eye 2020;44:1 35-41. Read the full text


Safety of Orthokeratology in myopic children

Hu et al conducted this retrospective study to evaluate the safety of Orthokeratology (OK) in children and explore the effect of factors such as age, refraction, and allergic conjunctivitis (AC) on corneal adverse events (AEs). Medical records of 260 patients (489 eyes) who wore OK lenses for myopia correction for more than one year were reviewed. The authors concluded that Orthokeratology is a safe option for children with myopia. Younger children with a higher degree of myopia and AC history are more prone to experiencing corneal AEs, and high refraction is the key risk factor for significant AEs.

Cont Lens Anterior Eye 2020;44:1 89-93. Read the full text


Bacterial contamination at multiple sites of CL users

This study aimed to investigate the presence and correlation between types of bacteria isolated from the palpebral conjunctiva, CL storage cases and the mobile phones of CL wearers. Waleed et al collected 189 swabs from 63 CL wearers. After performing biochemical tests, nine bacterial species were isolated and identified. The storage cases and mobile phones of the subjects were highly contaminated with pathogenic bacteria. To control transmission of infection, the authors recommend proper hygiene and usage of effective disinfectant for storage cases.

Cont Lens Anterior Eye 2020;44:1 62-66. Read the full text


Contact lens related complications in Ghana

To determine the complications associated with CL wear in Ghana, Kobia-Acquah et al retrospectively analysed records of 117 patients - 34 (29.1%) of them presented with CL-related complications. Whilst giant papillary conjunctivitis and corneal infiltrates were the top two reported complications, the top three common causes of CL complications were inappropriate lens cleaning, poor hygiene and overnight contact lens wear. Adherence to CL wear care regimen and good personal hygiene may prevent the majority of CL complications observed in in this study in Ghana.

Cont Lens Anterior Eye 2020;44:1 67-71. Read the full text


© International Association of Contact Lens Educators 2020

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