Research Update

Research Update Issue 15

March 2018

In this issue, we continue our efforts to understand myopia. A group from Denmark investigates the association of physical activity and myopia in Danish children 

March 2018  

Welcome to our monthly research update
Research Update is a resource available exclusively to IACLE and BCLA members to support your teaching and practice. Each month we send you a summary of some of the interesting findings appearing in peer-reviewed journals that month. Our aim is to help you keep up to date with the latest contact lens and anterior eye research, and to locate articles when you want to know more about a particular topic.
More information on Research Update and how to use it in your contact lens teaching here. Access archived issues via Member Login under Research.
Issue 15 – March 2018
In this issue, we continue our efforts to understand myopia. A group from Denmark investigates the association of physical activity and myopia in Danish children.

We include a review that presents updated tables of tear evaporation rates. Researchers in Spain evaluate the impact of a high-water daily disposable hydrogel lens on the ocular surface. We report on a study that attempts to understand the relationship between subjective ratings and satisfaction in CL wear. And a group from the US quantifies the tear elimination rate underneath silicone hydrogel and scleral gas-permeable contact lenses.

Many practitioners and researchers are intrigued by visual performance in keratoconus patients. A Spanish team assesses the vision quality achieved by corneo-scleral lenses in keratoconus. Finally, we include a study that evaluates the antimicrobial efficacy of various multipurpose disinfecting solutions in the presence of contact lenses and lens cases. Access the full text to see how each MPS performs.

Happy reading!

The IACLE Education Team
Journals reviewed in this issue  

  Acta Ophthalmologica 96:2
  Contact Lens & Anterior Eye Articles in press
  Clinical and Experimental Optometry 101:2
  Optometry and Vision Science 95:3
  Eye & Contact Lens 44:2

Physical activity and myopia: the CHAMPS Eye Study
This prospective study with longitudinal data on physical activity (PA) in 307 Danish children aged 14-17 years was conducted by Lundberg et al to determine associations between PA and myopia. PA was measured objectively by repeating ActiGraph accelerometer measurement four times with different intervals (1-2.5 years). The prevalence of myopia was 17.9% (SE ≤-0.5D) and mean axial length (AL) was 23.5+0.9mm. By logistic regression and slope analysis, authors found no association between PA and myopia.

Acta Ophthalmol 2018;96:2 134-141. Click here for abstract


Tear evaporation rates recalculated
This review by Wong et al presents updated tables of tear evaporation rates (TERs) using values from papers cited in a previous literature review (1941-2003), in addition to incorporating new studies published 2003-2016. Each paper cited in the literature review was checked against the TER reported. PubMed and Scopus searches were conducted to find papers published on tear evaporimetry since 2003. Two new tables of TERs are compiled to provide an accurate representation of the values reported in the original papers.

Cont Lens Anterior Eye 2018;DOI 10.1016/j.clae.2017.12.003. Click here for full text


Impact of high-water hydrogel DD on the ocular surface
A crossover study by Ruiz-Alcocer et al evaluates the impact on the ocular surface of a daily disposable (DD), high water content (78%) hydrogel CL compared with two silicone hydrogel DDs in 20 eyes of 20 patients. Lens thickness was measured to assess material stability during daily wear, and tear film osmolarity, tear meniscus area and central corneal thickness were also assessed. The hydrogel lens adequately resisted dehydration and did not impact significantly on tear film and corneal swelling after 1 day of use in first-time wearers, despite being the thinnest lens with the highest water content of those tested.

Clin Exp Optom 2018;101:2 188-192. Click here for abstract


Contact lens ratings and satisfaction
To understand the relationship between subjective ratings and satisfaction in CL wear, Diec et al performed retrospective analysis of two daily disposable CL trials on 64 participants 40 years or younger followed over 3 months. Subjective ratings included comfort (insertion, during the day and end of day), vision clarity and binary response (yes/no) for satisfaction with comfort and vision. Satisfaction in CL wear was influenced by both comfort and vision. A higher rating for comfort during the day compared with end of the comfort was required to attain satisfaction. Comfort on insertion was not associated with comfort satisfaction.

Optom Vis Sci 2018;95:3 256-263. Click here for abstract


Tear exchange: SiHys verses sclerals
To quantify tear elimination rate (ER) underneath silicone hydrogel (SiHy) and scleral gas-permeable (GP) CLs, Paugh et al recruited 14 soft SiHy and 12 scleral GP lens wearers. An objective fluorometer measured decay of fluorescein isothiocyanate dextran dye signal (70 kD MW) from which the tear ER in %/min was calculated. Data demonstrated significantly less ER in well-fit scleral GP CL wearers compared with soft SiHy CL wearers for both settling and longer wear periods. Also, slightly greater tear exchange was observed during the scleral GP CL settling period than later.

Eye & Contact Lens 2018;44:2 97-101. Click here for abstract


Visual quality with corneo-scleral lenses
To assess visual quality achieved by fitting corneo-scleral contact lenses (CScL) for keratoconus management, Montalt et al fitted CScL to 30 keratoconic patients and monitored 27 of them for 1 year. Objective eye examination was performed, and subjective visual quality and comfort, and wearing time reported. Significant differences were found in logMAR VA between the best spectacle-corrected VA and after CScL fitting. Total high-order aberrations decreased significantly. CScL were safe and healthy, providing optimal visual quality, comfort and prolonged usage times.

Cont Lens Anterior Eye 2018;DOI 10.1016/j.clae.2018.01.002. Click here for full text


Antimicrobial efficacy and compatibility of MPS
Gabriel et al used antimicrobial efficacy endpoint methodology (AEEMC), developed as a result of the 2006 Fusarium keratitis outbreak, to determine the compatibility of multipurpose disinfecting solutions (MPS), lens cases and hydrogel CLs, for disinfection against ISO-specified microorganisms and also S maltophilia. Six MPS were tested with three CL materials and lens cases. AEEMC results varied with challenge microorganism, CLs, and MPS. Hence it is important to evaluate MPS for compatibility with lenses and lens cases.

Eye & Contact Lens 2018;44:2 125-131. Click here for full text

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